KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP2B1
All Species:
36.36
Human Site:
Y421
Identified Species:
80
UniProt:
P63010
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P63010
NP_001025177.1
937
104553
Y421
I
R
D
I
F
R
K
Y
P
N
K
Y
E
S
I
Chimpanzee
Pan troglodytes
XP_001174136
940
104904
Y421
I
R
D
I
F
R
K
Y
P
N
K
Y
E
S
I
Rhesus Macaque
Macaca mulatta
XP_001105809
939
103490
Y421
I
K
D
I
F
R
K
Y
P
N
K
Y
E
S
V
Dog
Lupus familis
XP_867819
948
105775
F432
G
L
M
D
K
I
T
F
S
Y
V
Y
E
S
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBG3
937
104564
Y421
I
R
D
I
F
R
K
Y
P
N
K
Y
E
S
I
Rat
Rattus norvegicus
P62944
937
104534
Y421
I
R
D
I
F
R
K
Y
P
N
K
Y
E
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521247
904
100060
Y408
I
R
D
I
F
R
K
Y
P
N
K
Y
E
S
I
Chicken
Gallus gallus
XP_415772
951
105633
Y421
I
R
D
I
F
R
K
Y
P
N
K
Y
E
S
I
Frog
Xenopus laevis
NP_001080473
951
105601
Y421
I
R
D
I
F
R
K
Y
P
N
K
Y
E
S
I
Zebra Danio
Brachydanio rerio
NP_956213
951
105606
Y421
I
R
D
I
F
R
K
Y
P
N
K
Y
E
S
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P36000
726
81850
I254
D
S
L
E
A
Q
D
I
I
D
R
V
T
A
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
84
98.7
N.A.
99.8
100
N.A.
90.8
97.4
95.2
93.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
92.4
98.8
N.A.
99.8
100
N.A.
92.5
98.2
96.8
95.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
26.6
N.A.
100
100
N.A.
100
100
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
33.3
N.A.
100
100
N.A.
100
100
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
82
10
0
0
10
0
0
10
0
0
0
0
0
% D
% Glu:
0
0
0
10
0
0
0
0
0
0
0
0
91
0
0
% E
% Phe:
0
0
0
0
82
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
82
0
0
82
0
10
0
10
10
0
0
0
0
0
82
% I
% Lys:
0
10
0
0
10
0
82
0
0
0
82
0
0
0
0
% K
% Leu:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
82
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
82
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
73
0
0
0
82
0
0
0
0
10
0
0
0
0
% R
% Ser:
0
10
0
0
0
0
0
0
10
0
0
0
0
91
0
% S
% Thr:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
82
0
10
0
91
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _